He moved with his brother, Enoch, to Arkansas in 1849 and for a while engaged in agricultural pursuit. Later, Warren secured employment on a steamboat plying the waters of the Mississippi between St. Louis and New Orleans. He died of cholera during a scourge of that dread disease and his body was cast overboard near Natchez Mississippi. The exact date of this death is not known, but is thought to have been about the 1852.